A pharmacist told me that the FDA hasn’t recalled it, so it must be all right. Repatha has been shown to reduce the risk of heart attack and stroke (Sabatine et al, New England Journal of Medicine, May 4, 2017). Safeguards Before Taking Zetia. But what about ezetimibe (Zetia)? Vytorin lowered bad LDL cholesterol more than Zocor did but this did not lead to healthier arteries. Q. I have tried many statin drugs for cholesterol, but all gave me muscle pain and cramps. A. In the meantime, keep in mind that Zetia may cause muscle pain itself. The investigators note that many people stopped taking Vytorin or Zetia after they learned about this trial. Unfortunately, it didn’t reduce the risk of dying from cardiovascular causes. What Are Side Effects of Zetia? Evolocumab (Repatha) and alirocumab (Praluent) are PCSK9 inhibitors. When using Zetia, there is an increased possibility of myopathy (any illness affecting muscles or muscle tissue) and you must on time report any muscle pains, weakness, or softness to your doctor. As it turns out, Zetia may cause muscle problems, too. My experience with Zetia Imagine walking to a friend’s dinner party. Terry Graedon, PhD, is a medical anthropologist and co-host of The People’s Pharmacy radio show, co-author of The People’s Pharmacy syndicated newspaper columns and numerous books, and co-founder of The People’s Pharmacy website. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. She is a Fellow of the Society of Applied Anthropology. That increased their predicted risk of cardiovascular disease. We don’t know how the benefits and risks of PCSK9 inhibitors will play out over time. However, according to the Mayo Clinic, Zetia does have known side effects, one of which is dysphagia or trouble swallowing. He was not the only one to see ezetimibe in a less positive light. With so many drugs now available to lower cholesterol, people naturally would like to know about the benefits and risks of each. GAUSS-3 trial of evolocumab and ezetimibe. Most of the studies about Zetia in which Merck and Schering have published the results covered periods of only 12 weeks not enough time for liver problems to develop in most patients. There should be no danger switching to simvastatin, since it has been shown to be effective at lowering cholesterol and reducing the risk of heart attacks in people with heart disease (Ursoniu et al, Pharmacological Research, online June 9, 2017). Was on zetia for approx 4 months. Muscle side effects seem to be less common with Zetia than with the statin drugs, but Zetia may cause muscle problems. My doctor put me on Zetia and insists it can’t cause muscle pain since it is not absorbed into the blood stream. We have written quite a bit about the side effects of statins such as atorvastatin (Lipitor), rosuvastatin (Crestor) and simvastatin (Zocor). Rashes, lesions, alterations in blood tests, liver problems, stomach pain, pancreas inflammation, nausea, depression, hair loss, gallstones and inflammation of the gall bladder have all been experienced. Zetia (ezetimibe) is a lipid -lowering compound used to treat high cholesterol. My doctor tells me that until more is known, I should continue taking the prescribed medicine. Cardiologist Steven Nissen, MD, of the Cleveland Clinic said he was shocked by the results. At this time, these pricey medications are considered appropriate for treating people with familial high cholesterol. Sometimes, however, doctors find it hard to resist reaching into their toolbox for the newest thing that might help. As it turns out, Zetia may cause muscle problems, too. Consequently, we expect that other patients might end up taking them. It is Show 1031. 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