This condition is called disseminated zoster. In rare situations, a brain biopsy may be necessary to differentiate between ADEM and some other diseases that involve inflammation and damage to myelin. Diffuse idiopathic skeletal hyperostosis (DISH) is a bony hardening of ligaments in areas where they attach to your spine.Also known as Forestier's disease, this condition might not cause symptoms or require treatment. Disseminated intravascular coagulation (DIC) is a blood clotting disorder. Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free! It can also spread and cause disease throughout your body. Early disseminated Lyme disease is the phase of Lyme disease in which the bacteria that cause this condition have spread throughout your body. We describe a case of dissemin … Varicella-zoster is the virus that causes varicella (chicken pox), herpes zoster (shingles), and rarely, severe disseminated disease including diffuse rash, encephalitis, hepatitis, and pneumonitis. As well as causing the brain and spinal cord to become inflamed, ADEM also attacks the nerves of the central nervous system and damages their myelin insulation, which, as a result, destroys the white matter. Disseminated disease refers to a diffuse disease-process, generally either infectious or neoplastic. Disseminated zoster ca… Accessed 30 Nov. 2020. Disseminated herpes zoster is a complication of the herpes zoster virus. The term may sometimes also characterize connective tissue disease . The term “Valley fever” usually refers to Coccidioides infection in the lungs, but the infection can spread to other parts of the body in severe cases (this is called “disseminated coccidioidomycosis”). Acute disseminated encephalomyelitis (ADEM) is a rare kind of inflammation that affects the brain and spinal cord, usually in children. 'Nip it in the butt' or 'Nip it in the bud'? Often affecting individuals with compromised immunity, it occurs when the virus spreads throughout the body. Look it up now! Learn how and when to remove this template message, https://en.wikipedia.org/w/index.php?title=Disseminated_disease&oldid=951255225, Creative Commons Attribution-ShareAlike License, This page was last edited on 16 April 2020, at 07:43. It is often triggered by a viral infection or (very rarely) specific non-routine Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by activation of coagulation pathways, resulting in formation of intravascular thrombi and depletion of platelets and coagulation factors. 'All Intensive Purposes' or 'All Intents and Purposes'? Disseminated disease refers to a widespread or diffuse disease-process, generally either infectious or neoplastic, but sometimes also referring to connective tissue disease. Disseminated intravascular coagulation (DIC) is a rare, life-threatening condition. A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to "seed" other areas of the body. We report a case of a 60-year-old woman whose initial complaints of an erythematous, “burning” rash and flu-like symptoms led to several laboratory tests with no … : widely dispersed in a tissue, organ, or the entire body disseminated gonococcal disease … overt disease sets in, first as chronic infections of the skin and mucous membranes and then as disseminated, systemic infections. The term may sometimes also characterize connective tissue disease. It can originate from and cause damage to the microvasculature, which if sufficiently severe, can produce organ dysfunction. Cutaneous manifestations of malignant lung disease Apart from skin metastases and infections of the skin secondary to impaired host defence consequent upon disseminated cancer, there are several skin conditions that, although not malignant themselves, are sometimes associated with systemic cancer, including bronchopulmonary carcinoma. But what if this normal blood clotting process went into overdrive? The timely diagnosis of early disseminated Lyme disease presenting as multiple secondary erythema migrans lesions is sometimes delayed because this stage is infrequently encountered in a general practice. Mycobacterium avium complex (MAC) is widely distributed in the environment, and exposure to the organisms is common. Can you spell these 10 commonly misspelled words? There are generally two types that are common in humans — those … A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to "seed" other areas of the body. Disseminated disease refers to a diffuse disease -process, generally either infectious or neoplastic. If it does cause symptoms, the most common are mild to moderate pain and stiffness in your upper back. A disseminated infection, for example, has extended beyond its origin or nidus and involved the bloodstream to “seed” other areas of the body. The rash most commonly appears on the trunk along a thoracic dermatome. Similarly, one can view metastatic cancer as a disseminated infection in that it has extended into the bloodstream or into the lymphatic system and thus "seeded" distant sites (a process known as metastasis). In the United States, histoplasmosis commonly occurs in the Mississippi and Ohio river valleys, tho… What made you want to look up disseminated? More from Merriam-Webster on disseminated, Thesaurus: All synonyms and antonyms for disseminated, Nglish: Translation of disseminated for Spanish Speakers, Britannica English: Translation of disseminated for Arabic Speakers. Multiple Sclerosis Definition Multiple sclerosis (MS) is a chronic autoimmune disorder affecting movement, ensation, and bodily functions. This generally occurs only in people with compromised or suppressed immune systems. Immun… A disseminated disease is a type of disease that has spread from its initial point of origin or contact in the body to other regions that were not its specific target of attack. Our Word of the Year 'pandemic,' plus 11 more. See more. Disseminated disease refers to a diffuse disease-process, generally either infectious or neoplastic. Disseminated intravascular coagulation (DIC) is a serious disorder in which the proteins that control blood clotting become overactive. Histoplasmosis is an infection caused by breathing in spores of a fungus often found in bird and bat droppings. People with herpes zoster most commonly have a rash in one or two adjacent dermatomes (localized zoster). You don’t give it a second thought. It may be a secondary complication of any of numerous obstetrical, surgical, infectious, hemolytic, and neoplastic disorders, all of which activate in some way the intrinsic coagulation … Disseminated definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. In the early stages of the condition, DIC causes your blood … It can infect one part of your body, like your lungs, bones, or intestines. It damages the … Disseminated disease is often contrasted with localized disease. — Robert R. Redfield et al., Scientific American, October 1988 — see acute disseminated … While there are systemic infections that can affect the entire body at once, doctors will reserve the term for those infections that are normally constrained to a specific site. Delivered to your inbox! The fungus is known to live in the soil in the southwestern United States and parts of Mexico and Central and South America. Post the Definition of disseminated to Facebook, Share the Definition of disseminated on Twitter, … overt disease sets in, first as chronic infections of the skin and mucous membranes and then as. However, while many persons are transiently colonized with MAC, disease due to MAC is rare. DISH can also affect your neck and lower back, and some people have DISH in other areas, such as shoulders, elbows, knees and heels.DISH can be progressive. noun a chronic progressive disease of the central nervous system characterized by loss of some of the myelin sheath surrounding certain nerve fibres and resulting in speech and visual disorders, tremor, muscular incoordination, partial … Disseminated disease is most often seen in immunocompromised patients. This article summarizes our understanding of the pathophysiologic mechanisms that lead to disseminated MAC disease. Usually, it propagates through the blood supply or lymph system that carries white blood cells in plasma to fight infections. Spontaneous bleeding may occur. Sometimes necessitating hospitalization, treatment for disseminated herpes zoster involves the administration of medications, including steroidal and antiviral drugs, to ease symptoms and prevent complications. to spread or give out something, especially news, information, ideas, etc., to a lot of people: One of the organization's aims is to disseminate information about the disease. Incidence rates have ranged from 0.06 to 1.56 cases per million vaccinated, and mortality rates have remained at ≈60% (1–7).Of 946 patients with primary immunodeficiency, including 29 with severe combined immunodeficiencies, diagnosed from 1980 … disseminated intravascular coagulation (DIC) a bleeding disorder characterized by abnormal reduction in the elements involved in blood clotting due to their use in widespread intravascular clotting. Thrombi may lead to vascular obstruction/ischemia and multiorgan failure. Herpes zoster is the reactivation of the virus and its spread from a single dorsal root or cranial nerve ganglion to the corresponding dermatome and … [4] Symptoms may include chest pain, shortness of breath, leg pain, problems speaking, or problems moving parts of the body. The term may sometimes also characterize connective tissue disease. Persons with AIDS are particularly susceptible to MAC disease, and in such persons the organisms disseminate widely. Test Your Knowledge - and learn some interesting things along the way. It is caused by destruction of the myelin insulation covering nerve fibers (neurons) in the central nervous system (brain and spinal cord). The subcommittee on DIC of the International Society on Thrombosis and Haemostasis has suggested the following definition for DIC: An acquired syndrome characterized by the intravascular activation of coagulation with loss of localization arising from different causes. You cut your finger or nick your leg and your body gets to work to stop the bleeding. Histoplasmosis is most commonly transmitted when these spores become airborne, often during cleanup or demolition projects.Soil contaminated by bird or bat droppings also can transmit histoplasmosis, so farmers and landscapers are at a higher risk of contracting the disease. To the Editor: Disseminated bacillus Calmette-Guérin (BCG) infection has been noted in patients with primary immunodeficiency. Less commonly, the rash can be more widespread and affect three or more dermatomes. This is localized infection. Please tell us where you read or heard it (including the quote, if possible). Disseminated disease has two main clinical presentations (overlap does occur) Chronic adult form: pulmonary and extrapulmonary (mucocutaneous often) involvement Acute to subacute juvenile form: reticuloendothelial system involvement (liver, spleen, lymph nodes); pulmonary complaints are minimal As it w… Which word describes a musical performance marked by the absence of instrumental accompaniment. As clotting factors and platelets are used up, bleeding may occur. Disseminate definition, to scatter or spread widely, as though sowing seed; promulgate extensively; broadcast; disperse: to disseminate information about preventive medicine. The rash does not usually cross the body’s midline. A disseminated infection is one in which a localized infection spreads (disseminates) from one area of the body to other organ systems. 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